Malegra DXT Plus is a combination medication commonly used to help manage erectile dysfunction (ED) and premature ejaculation (PE) in men. It typically contains sildenafil citrate and duloxetine. Sildenafil helps improve erectile function by increasing blood flow to the penis, while duloxetine affects certain chemical signals in the nervous system that may help with ejaculation control. Sildenafil works by inhibiting the PDE5 enzyme, allowing blood vessels in the penis to relax and improving circulation during sexual stimulation.
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