Malegra DXT is marketed as a combination medicine containing sildenafil and duloxetine. Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED), while duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used for several medical conditions. Because combination products can vary by market and manufacturer, the exact ingredients and strengths should always be confirmed on the product packaging. Sildenafil works by increasing blood flow to the penis during sexual stimulation, helping men achieve and maintain an erection. It does not increase sexual desire and does not normally produce an erection without sexual stimulation.
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